Rejuvenation Treatments

Polynucleotides

About this treatment

Polynucleotides, often referred to as the “salmon sperm facial,” are long chains of nucleotides—the building blocks of DNA and RNA—typically purified from salmon or trout. This revolutionary treatment offers longer-lasting results than many other skin therapies. When injected into the skin via microdroplets, polynucleotides stimulate fibroblasts to boost collagen and elastin production, encourage cellular repair, improve hydration, reduce inflammation, and provide antioxidant benefits. Treatments usually involve 2–4 sessions spaced 3–4 weeks apart, with maintenance recommended every 6–12 months. Results generally begin to appear within 4–8 weeks, with full effects visible after 12 weeks or more. The benefits include firmer, tighter skin through collagen and elastin stimulation, improved tone and texture with cellular repair, plumper, smoother skin from enhanced hydration, and calmer, less inflamed skin thanks to anti-inflammatory and antioxidant properties. Polynucleotides are suitable for delicate areas such as the under-eyes, neck, décolletage, hands, and even the scalp.

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With over 50 years of combined experience.

  • Qualified General Practitioner

  • Qualified Aesthetic Doctor

  • Registered with the General Medical Council (GMC)

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Frequently asked questions

Are polynucleotides safe?

Yes, they are considered biocompatible and safe when administered by a qualified and experienced practitioner.
However, they are not suitable for individuals with fish or shellfish allergies.

Common and temporary side effects include mild redness, swelling, or bruising at the injection sites.
Downtime is minimal, with most people able to return to normal activities immediately.

A topical numbing cream is often applied to minimize discomfort.
A course of treatments is generally recommended for best results.
Results are gradual, with improvements noticed within weeks and peaking over several months.